Simparica TRIO for Dog

Simparica Trio – Broad-Spectrum Treatment for Dogs

Simparica Trio for Dogs is a tasty pork liver-flavored treatment that provides comprehensive protection against external and internal parasites. Just one chew every month offers triple protection against fleas & ticks, heartworm disease and intestinal worms. This all-in-one parasite protection is the only combination canine treatment proven to kill 6 species of ticks, according to Zoetis, USA. When used as directed, Simparica Trio is shown to deliver broad-spectrum protection against:

Fleas

• Kills adult fleas before they can lay eggs.
• Indicated for the treatment and prevention of flea infestations.
• Helps reduce the signs of flea allergy dermatitis by eliminating fleas.
• Helps reduce the risk of flea tapeworm (Dipylidium caninum) infections by killing fleas.

Ticks

• Treats & controls tick infestations of American dog ticks, black-legged ticks, brown dog ticks, Gulf Coast ticks, Lone Star ticks, & Asian longhorned ticks.

Heartworms

• Indicated for the prevention of heartworm disease caused by Dirofilaria immitis.

Intestinal worms

• Treats & controls roundworm (Toxocara canis and Toxascaris leonina) and hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.

Lyme disease

• Indicated for the prevention of Lyme disease (Borrelia burgdorferi) infections by killing black-legged vector ticks.

Indicated for

Puppies and dogs 8 weeks of age or older, weighing 2.8 lbs or greater.

• Broad-spectrum treatment: Safeguards dogs from external and internal parasites.
• Trio of ingredients: Formulated using three active ingredients - sarolaner, moxidectin, and pyrantel - for all-round coverage.
• Triple protection: Protects against fleas & ticks, heartworm disease and intestinal worms.
• Flavored chew: Tasty pork liver-flavored chew dogs enjoy and accept without hassle.
• Comprehensive tick coverage: A single chew is effective against six different species of ticks.
• Safe for young dogs: Suitable for puppies from 8 weeks of age.
• Convenient dosing: Can be administered directly or with the dog's favorite food.

• Weigh your dog and choose the pack that closely matches their weight.
• This chew should be administered orally, as a single dose, once every month. It can be administered with or without food.
• When administering with food, observe your dog closely and ensure the dog takes the complete dose.
• When using this chew for flea, tick and flea tapeworm protection, you can begin treatment with Simparica Trio at any time of the year, but continue throughout the year without interruption.
• To prevent heartworm disease, administer Simparica Trio all year. Begin treatment at least within one month after the dog's first exposure to mosquitoes and continue until at least one month after the dog's last seasonal exposure.
• If you forget administering a dose, give one dose immediately and resume the monthly schedule.

Sarolaner, Moxidectin, and Pyrantel

You should keep these chews out of the reach of children, uninformed people and pets. If ingested accidentally, consult a physician. Wash your hands thoroughly after handling the treatment.

Field studies referenced in the product label suggest that these chews can be used with vaccines, anthelmintics, antimicrobials, analgesics, antiprotozoals, anesthetic agents and NSAIDs without any side effects.

Precautions

Test your dog for existing heartworms before beginning the treatment with Simparica Trio. Infected dogs should be treated to remove adult heartworms at the discretion of a veterinarian.

The safe use of this flea, tick and worm treatment has not been evaluated in breeding, lactating and pregnant dogs. It is indicated you use these chews with caution in dogs with a history of seizures or other neurologic disorders. Consult a vet before use.

Contraindications

Simparica Trio is not indicated for puppies and dogs under 8 weeks of age or below 2.8 lbs of body weight. It is not for use in humans or any other animal species.

Storage Instructions

Store at or below 30°C (86°F).

What is Simparica Trio?

Simparica Trio is a tasty pork liver-flavored monthly chewable treatment, designed to protect your dog from internal and external parasites, including fleas, ticks, heartworm disease and intestinal worms.

What parasites does this oral chewable protect my dog against?

When used as directed, this oral chew kills adult fleas, treats and prevents flea infestations and treats and controls 6 tick species. Additionally, the oral treatment prevents heartworm disease and treats and controls roundworm and hookworm infections. It is also indicated to prevent Lyme disease infections by killing black-legged vector ticks.

How does Simparica Trio work?

This monthly chew for dogs contains sarolaner, moxidectin and pyrantel as its active ingredients. After administration, the ingredients are quickly absorbed into the dog's bloodstream and are distributed to tissue fluids, just under the dog's skin. Sarolaner is effective against external parasites, such as fleas and ticks. Moxidectin works to disrupt the neurotransmission of relevant parasites, preventing heartworm disease. Pyrantel treats and controls intestinal worms (roundworms and hookworms).

Is Simparica Trio really effective?

One dose of Simparica Trio is shown to 100% effective in preventing the development of heartworm disease when given as indicated, according to lab studies referenced in the label. These chews demonstrate complete effectiveness against fleas at eight hours post-administration and reduce the number of live ticks by more than 90% within 24 hours of infestations, as per another lab study referenced in the label.

Is Simparica Trio safe for my puppy?

Simparica Trio is indicated for use in puppies and dogs from 8 weeks of age, weighing 2.8 lbs or greater.

How is Simparica Trio different from Simparica?

Simparica contains one active ingredient, sarolaner. It is effective against external parasites, such as fleas and ticks. Simparica Trio is formulated with three active ingredients, sarolaner, moxidectin and pyrantel. As a result, it protects against both internal and external parasites, including fleas, ticks, heartworm disease, roundworms and hookworms. Both these treatments are indicated to prevent Lyme disease infections by killing black-legged vector ticks.

What ticks is Simparica Trio effective against?

This monthly chew for dogs is effective against 6 tick species, including American dog ticks, black-legged ticks, brown dog ticks, Gulf Coast ticks, lone star ticks and Asian longhorned ticks.

How do I replace my dog's heartworm preventive with Simparica Trio?

It is recommended that you consult a vet before replacing your dog's heartworm preventive. Give the first dose of Simparica Trio within one month of the last dose of your dog's previous preventive (when replacing a monthly treatment), ensuring your dog is protected throughout the transition.

I've missed giving my dog Simparica Trio. What should I do now?

When you miss a dose, give one chew immediately and resume with the monthly schedule.